Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 95
2025
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Pseudomonas rossensis sp. nov., a novel psychrotolerant species produces antimicrobial agents targeting resistant clinical isolates of Pseudomonas aeruginosa
Current Research in Microbial Sciences, year: 2025, volume: 8, edition: 2025, DOI
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Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer
MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI
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Tau-tubulin kinase 2 restrains microtubule-depolymerizer KIF2A to support primary cilia growth
Cell Communication and Signaling, year: 2025, volume: 23, edition: 1, DOI
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TP53 detection based on electrochemical genosensors with different types of gold nanoparticles
Microchemical Journal, year: 2025, volume: 209, edition: February 2025, DOI
2024
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37th Central European NMR Meeting, NMR Valtice 2024
Year: 2024, type: Conference
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Advanced characterization of nano and biomaterials using AFM and Raman microscopy
Year: 2024, type: Conference abstract
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Advanced Imaging and Mechanical Profiling of Biological Samples with Confocal and Atomic Force Microscopy
Year: 2024, type: Conference abstract
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AFM Spectroscopy for the Study of Lipid Bilayer Stability and Morphology
Year: 2024, type: Conference abstract
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CF Day 2023
Year: 2024, type: Popularization text
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Comparison of phosphopeptide enrichment and LC-MS/MS acquisition methods to study cancer phosphoproteome
Year: 2024, type: Conference abstract