Project information
Usage of urinary/tissue microRNAs to increase PSA specificity and distinguish between indolent and aggressive forms of prostate cancer

Information

This project doesn't include Faculty of Science. It includes Central European Institute of Technology. Official project website can be found on muni.cz.

Project Identification

NV18-03-00360

Project Period

5/2018 - 12/2022

Investor / Pogramme / Project type

Ministry of Health of the CR

Ministry of Health Research Programme 2015 - 2022

MU Faculty or unit

Central European Institute of Technology

prof. RNDr. Ondřej Slabý, Ph.D.

Cooperating Organization

Masaryk Memorial Cancer Institute Brno

Responsible person doc. MUDr. Michal Staník, Ph.D.

Cílem projektu je vytvořit diagnostický panel cirkulujících miRNA v moči pacientů s PCa umožňující jednak zvýšení specificity PSA a zároveň odlišení indolentní a agresivní formy karcinomu prostaty, který by bezpečně identifikoval pacienty benefitující z radikální protinádorové terapie.

Publications

Total number of publications: 4

2023

A tissue miRNA expression pattern is associated with disease aggressiveness of localized prostate cancer

JURÁČEK Jaroslav BOUDNÁ Marie STANÍK Michal RUČKOVÁ Michaela TRACHTOVÁ Karolína MALČÍKOVÁ Hana LŽIČAŘOVÁ Eva BARTH Dominik A PICHLER Martin SLABÝ Ondřej

Article in Periodical

Prostate, year: 2023, volume: 83, edition: 4, DOI
Combination of Urinary MiR-501 and MiR-335 With Current Clinical Diagnostic Parameters as Potential Predictive Factors of Prostate Biopsy Outcome

JURÁČEK Jaroslav MĄDRZYK Marie TRACHTOVÁ Karolína RUČKOVÁ Michaela BOHOŠOVÁ Júlia BARTH Dominik A. PICHLER Martin STANÍK Michal SLABÝ Ondřej

Article in Periodical

CANCER GENOMICS & PROTEOMICS, year: 2023, volume: 20, edition: 3, DOI

2022

Urinary microRNAs and Their Significance in Prostate Cancer Diagnosis: A 5-Year Update

JURÁČEK Jaroslav MĄDRZYK Marie STANÍK Michal SLABÝ Ondřej

Article in Periodical

CANCERS, year: 2022, volume: 14, edition: 13, DOI

2020

Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas

HULSTAERT E. MORLION A. COBOS F.A. VERNIERS K. NUYTENS J. VANDEN EYNDE E. YIGIT N. ANCKAERT J. GEERTS A. HINDRYCKX P. JACQUES P. BRUSSELLE G. BRACKE K.R. MAES T. MALFAIT T. DERVEAUX T. NINCLAUS V. VAN CAUWENBERGH C. ROELENS K. ROETS E. HEMELSOET D. TILLEMAN K. BROCHEZ L. KUERSTEN S. SIMON L.M. KARG S. KAUTZKY-WILLERS A. LEUTNER M. NOHAMMER C. SLABÝ Ondřej PRINS R.W. KOSTER J. LEFEVER S. SCHROTH G.P. VANDESOMPELE J. MESTDAGH P.

Article in Periodical

Cell Reports, year: 2020, volume: 33, edition: 13, DOI