Mgr. Jan Brezovský, Ph.D.

2017

• Enzyme Tunnels and Gates As Relevant Targets in Drug Design

  MARQUES Sérgio Manuel DANIEL Lukáš BURYŠKA Tomáš PROKOP Zbyněk BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Article in Periodical

  MEDICINAL RESEARCH REVIEWS, year: 2017, volume: 37, edition: 5, DOI

• FireProt 1.0

  MUSIL Miloš ŠTOURAČ Jan BENDL Jaroslav BREZOVSKÝ Jan PROKOP Zbyněk ZENDULKA J. MARTÍNEK Tomáš BEDNÁŘ David DAMBORSKÝ Jiří

  Year: 2017

• FireProt: Web Server for Automated Design of Thermostable Proteins

  MUSIL Miloš ŠTOURAČ Jan BENDL Jaroslav BREZOVSKÝ Jan PROKOP Zbyněk ZENDULKA Jaroslav MARTÍNEK Tomáš BEDNÁŘ David DAMBORSKÝ Jiří

  Article in Periodical

  Nucleic Acids Research, year: 2017, volume: 45, edition: W1, DOI

• Pyrazolotriazines as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit, Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: European Patent Office, state: Germany, patent's number: EP2957562, year: 2017

2016

• CAVER: Algorithms for Analyzing Dynamics of Tunnels in Macromolecules

  PAVELKA Antonín ŠEBESTOVÁ Eva KOZLÍKOVÁ Barbora BREZOVSKÝ Jan SOCHOR Jiří DAMBORSKÝ Jiří

  Article in Periodical

  IEEE/ACM Transactions on Computational Biology and Bioinformatics, year: 2016, volume: 13, edition: 3, DOI

• Discovery of Novel Haloalkane Dehalogenase Inhibitors

  BURYŠKA Tomáš DANIEL Lukáš KUNKA Antonín BREZOVSKÝ Jan DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  Applied and Environmental Microbiology, year: 2016, volume: 82, edition: 6, DOI

• Engineering a de Novo Transport Tunnel

  BREZOVSKÝ Jan BABKOVÁ Petra DEGTJARIK Oksana FOŘTOVÁ Andrea GÓRA Artur Wiktor IERMAK L. ŘEZÁČOVÁ Petra DVOŘÁK Pavel KUTÁ-SMATANOVÁ Ivana PROKOP Zbyněk CHALOUPKOVÁ Radka DAMBORSKÝ Jiří

  Article in Periodical

  ACS Catalysis, year: 2016, volume: 6, edition: 11, DOI

• HotSpot Wizard 2.0: Automated Design of Site-Specific Mutations and Smart Libraries in Protein Engineering

  BENDL J. ŠTOURAČ Jan ŠEBESTOVÁ Eva VÁVRA Ondřej MUSIL Miloš BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Article in Periodical

  Nucleic Acids Research, year: 2016, volume: 44, edition: W1, DOI

• PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions

  BENDL Jaroslav MUSIL Miloš ŠTOURAČ Jan ZENDULKA Jaroslav DAMBORSKÝ Jiří BREZOVSKÝ Jan

  Article in Periodical

  PLOS COMPUTATIONAL BIOLOGY 12: e100496, year: 2016, volume: 12, edition: 5, DOI

• Role of Tunnels and Gates in Enzymatic Catalysis

  MARQUES Sérgio Manuel BREZOVSKÝ Jan DAMBORSKÝ Jiří

  Chapter of a book

  UNDERSTANDING ENZYMES: FUNCTION, DESIGN, ENGINEERING, AND ANALYSIS, year: 2016, number of pages: 43 s.