doc. Mgr. Karel Souček, Ph.D.

2017

• Diastereoselective Flexible Synthesis of Carbocyclic C Nucleosides

  MAIER Lukáš KHIRSARIYA PrashantKumar HYLSE Ondřej ADLA Santosh Kumar ČERNOVÁ Lenka POLJAK Michal KRAJČOVIČOVÁ Soňa WEIS Erik DRÁPELA Stanislav SOUČEK Karel PARUCH Kamil

  Article in Periodical

  The Journal of Organic Chemistry, year: 2017, volume: 82, edition: 7, DOI

• Flow cytometric analysis of nucleoside transporters activity

  DRÁPELA Stanislav FEDR Radek KHIRSARIYA PrashantKumar PARUCH Kamil SOUČEK Karel

  Conference abstract

  Year: 2017, type: Conference abstract

• Hematological Profile of Untreated or Ionizing Radiation-Exposed Cyclooxygenase-2-Deficient Mice

  HOFER M. HOFEROVA Z. DUŠEK Ladislav SOUČEK Karel GRUZDEV A.

  Article in Periodical

  Physiological research, year: 2017, volume: 66, edition: 4

• Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

  HERŮDKOVÁ Jarmila PARUCH Kamil KHIRSARIYA PrashantKumar SOUČEK Karel KRKOŠKA Martin VONDÁLOVÁ BLANÁŘOVÁ Olga SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Neoplasia, year: 2017, volume: 19, edition: 10, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI

2016

• Cisplatin or LA-12-mediated stimulation of TRAIL-induced apoptosis in human prostate cancer cells involves Bax/Bak-dependent mitochondria activation

  VONDÁLOVÁ BLANÁŘOVÁ Olga HERŮDKOVÁ Jarmila ŠAFAŘÍKOVÁ Barbora KRKOŠKA Martin TOMÁNKOVÁ Silvie PERNICOVÁ Zuzana SOUČEK Karel BOUCHAL Jan KHARAISHVILI G KRÁL M SOVA P HOFMANOVÁ Jiřina KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2016, type: Conference abstract

• Comparison of the ATH and 2CXM models using low- and high-molecular-weight contrast agents in DCE-MRI

  JÍŘÍK Radovan TAXT Torfin SOUČEK Karel KRATOCHVÍLA Jiří MACÍČEK Ondřej DRAŽANOVÁ Eva STARČUK Zenon

  Conference abstract

  Year: 2016, type: Conference abstract

• Direct comparison of ASL and DCE-MRI in a mouse model of cancer

  GROSSOVÁ Lucie JIŘÍK Radovan DRAŽANOVÁ Eva SOUČEK Karel STARČUK Zenon

  Conference abstract

  Year: 2016, type: Conference abstract

• Inhibition of Chk1 enhances colon cancer cell sensitivity to apoptosis induced by platinum (IV) complex LA-12.

  LAUKOVÁ Jarmila VONDÁLOVÁ BLANÁŘOVÁ Olga PARUCH Kamil SOUČEK Karel SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2016, type: Conference abstract

• KSR proteins link metabolic changes to the MAPK/ERK pathway

  VERLANDE Amandine POTĚŠIL David ZDRÁHAL Zbyněk KRAFČÍKOVÁ Michaela TRANTÍREK Lukáš SOUČEK Karel TRNKA Jan KOLCH W ELKALAF M

  Appeared in Conference without Proceedings

  Year: 2016, type: Appeared in Conference without Proceedings