prof. RNDr. Jan Vondráček, Ph.D.

2025

• Evaluation of mitochondrial, ER and oxidative stress endpoints induced by polycyclic aromatic hydrocarbons in human hepatocyte-like cells

  VEČEŘOVÁ Kateřina LNĚNIČKOVÁ Anna PĚNČÍKOVÁ Kateřina PETRÁŠ Jiří MACHALA Miroslav VONDRÁČEK Jan

  Conference abstract

  Year: 2025, type: Conference abstract

• Inhibition of lactosylceramide synthases B4GALT5 or B4GALT6 enhances oxaliplatin-induced cell death in colon cancer cells

  LUJKA Barbora ŠOŠOLÍKOVÁ Tereza VÁZQUEZ GÓMEZ Gerardo KOVÁČ Ondrej MACHALA Miroslav HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2025, type: Conference abstract

• Polycyclic aromatic hydrocarbons (PAHs) acting as AhR ligands may alter glucose production and/or transport in human hepatocyte-like HepaRG cells

  PETRÁŠ Jiří LNĚNIČKOVÁ Anna PĚNČÍKOVÁ Kateřina MACHALA Miroslav LECLAIR Heloise EZAN Frederic LANGOUËT Sophie VONDRÁČEK Jan

  Conference abstract

  Year: 2025, type: Conference abstract

2024

• AhR-activating polycyclic aromatic hydrocarbons and disruption of glucose metabolism in hepatocyte-like cells

  PETRÁŠ Jiří LNĚNIČKOVÁ Anna ŠIMEČKOVÁ Pavlína MACHALA Miroslav VONDRÁČEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract

• AhR-activating polycyclic aromatic hydrocarbons disrupt metabolic pathways in human hepatocyte-like cells

  VONDRÁČEK Jan PETRÁŠ Jiří ŠIMEČKOVÁ Pavlína PĚNČÍKOVÁ Kateřina DVOŘÁK Zdeněk MACHALA Miroslav

  Conference abstract

  Year: 2024, type: Conference abstract

• Aryl hydrocarbon receptor as a drug target in advanced prostate cancer therapy - obstacles and perspectives

  PROCHÁZKOVÁ Jiřina KAHOUNOVA Zuzana VONDRÁČEK Jan SOUČEK Karel

  Article in Periodical

  TRANSCRIPTION-AUSTIN, year: 2024, DOI

• Effects of AhR-activating PAHs on glucose transport and metabolism in liver cells

  PETRÁŠ Jiří LNĚNIČKOVÁ Anna MACHALA Miroslav VONDRÁČEK Jan

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

• Evaluation of potential role of the aryl hydrocarbon receptor in cellular stress response to benzo[k]fluoranthene exposure in liver cell lines

  LNĚNIČKOVÁ Anna PĚNČÍKOVÁ Kateřina MACHALA Miroslav VONDRÁČEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract

• Generation of Caco-2 AhR KO cell model to study the role of AhR in gut inflammatory responses and epithelial barrier integrity

  JAKUBCOVÁ Klára VÁZQUEZ-GÓMEZ Gerardo SLÁDEKOVÁ Lucia DVOŘÁK Zdeněk VONDRÁČEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract

• The impact of inhibition of lactosylceramide synthases B4GALT5 and B4GALT6 on colon cancer cell death

  LUJKA Barbora ŠOŠOLÍKOVÁ Tereza VÁZQUEZ GÓMEZ Gerardo KOVÁČ Ondrej MACHALA Miroslav HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2024, type: Conference abstract