prof. RNDr. Daniel Růžek, Ph.D.

2025

• A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases.

  KRISHNAMURTHY HK JAYARAMAN V KRISHNA K WANG T BEI K CHANGALATH C MATILDA S AJ Rai WELC-FALĘCIAK R PAWEŁCZYK A LS Blanton CHRDLE A FOŘTOVÁ Andrea RŮŽEK Daniel GK Nasrallah ABU-RADDADI LJ AL-SADEQ DW MAA Abdallah LILLERI D FORNARA C D'ANGELO P FURIONE M SÖDERLUND-VENERMO M HEDMAN K CHOCHLAKIS D MAKRIDAKI E NTOULA A PSAROULAKI A ESCÁRCEGA-ÁVILA A JJ Rajasekaran

  Article in Periodical

  Sci Rep., year: 2025, volume: 15, edition: 1, DOI

• AntiviralDB: an expert-curated database of antiviral agents against human infectious diseases

  HUANG Jie SONG Qixiang ZHANG Pan DENG Lei GAO Feng DENG Yelin KROL Ewelina RŮŽEK Daniel KHOURI Ricardo DE CLERCQ Erik LI Guangdi

  Article in Periodical

  mBio, year: 2025, volume: 16, edition: 10, DOI

• Detection of tick-borne encephalitis virus RNA in patient samples at different stages of infection

  KRIHA Michal Frantisek KAMIS Jan DVORAKOVA Marketa TARDY Luc ELSTEROVA Jana TEISLEROVA Dana CHRDLE Ales PALUS Martin RŮŽEK Daniel HONIG Vaclav

  Article in Periodical

  Journal of Infection, year: 2025, volume: 90, edition: 5, DOI

• Enhanced RNAi does not provide efficient innate antiviral immunity in mice

  KULMANN Marcos Iuri Roos TABORSKA Eliska BENKÖOVA Brigita PALUS Martin DROBEK Ales HORVAT Filip PASULKA Josef MALIK Radek SALYOVA Eva HÖNIG Václav PELLEROVA Michaela BORSANYIOVA Maria NEDVEDOVA Lenka STEPANEK Ondrej BOPEGAMAGE Shubhada RŮŽEK Daniel SVOBODA Petr

  Article in Periodical

  Nucleic Acids Research, year: 2025, volume: 53, edition: 1, DOI

• Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain.

  BERÁNKOVÁ Michaela HOLOUBEK Jiří HÖNIG Václav MATUSOVA Zuzana PALUS Martin SALÁT Jiří KRAYEM Imtissal VOJTISKOVA Jarmila SVOBODA Pavel PRANCLOVA Veronika VALIHRACH Lukas DEMANT Peter LIPOLDOVA Marie RŮŽEK Daniel

  Article in Periodical

  Journal of Neuroinflammation, year: 2025, volume: 22, edition: 1, DOI

• Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

  SUYAMA Satoshi BOXALL Sally GRACE Benjamin FOŘTOVÁ Andrea PÝCHOVÁ Martina KRBKOVÁ Lenka MANDAL Rupasri WISHART David GRIFFIN Diane E RŮŽEK Daniel GOONAWARDANE Niluka

  Article in Periodical

  Journal of neuroinflammation, year: 2025, volume: 22, edition: 1, DOI

• Influence of the pre-membrane and envelope proteins on structure, pathogenicity, and tropism of tick-borne encephalitis virus.

  ROSENDAL Ebba BISIKALO Kyrylo WILLEKENS Stefanie MA LINDGREN Marie HOLOUBEK Jiří SVOBODA Pavel LAPPALAINEN Amanda KÖNIGHOFER Ebba MIRGORODSKAYA Ekaterina NORDÉN Rickard MORINI Federico ROSENBAUM William RŮŽEK Daniel AHLGREN Ulf ANASTASINA Maria MERITS Andres BUTCHER Sarah J NILSSON Emma ÖVERBY Anna K

  Article in Periodical

  Journal of Virology, year: 2025, volume: 99, edition: 9, DOI

• Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious

  HOLOUBEK Jiří SALÁT Jiří MATKOVIC Milos BEDNÁŘ Petr NOVOTNÝ Pavel HRADILEK Martin MAJEROVÁ Taťána ROSENDAL Ebba EYER Luděk FOŘTOVÁ Andrea BERÁNKOVÁ Michaela BELL-SAKYI Lesley ÖVERBY Anna K CAVALLI Andrea BONOMI Massimiliano REY Felix A RŮŽEK Daniel

  Article in Periodical

  Nature Communications, year: 2025, volume: 16, edition: 1, DOI

• Lenacapavir: A capsid inhibitor for HIV-1 treatment and prevention

  DE CLERCQ Erik ZHANG Yuya LI Guangdi DENG Yelin KHOURI Ricardo RŮŽEK Daniel KRÓL Ewelina TAN Li

  Article in Periodical

  Biochemical Pharmacology, year: 2025, volume: 240, edition: October, DOI

• Membrane-Active Singlet Oxygen Photogenerators as a Paradigm for Broad-Spectrum Antivirals: The Case of Halogenated (BOron)-DIPYrromethenes

  MARYEWSKI Xenia A. KRASILNIKOV Maxim S. STRAKOVÁ Petra HOLOUBEK Jiří FRČKOVÁ Tereza PANINA Irina S. KRYLOV Nikolay A. GVOZDEV Daniil A. DENISOV Vladislav S. SEMENOV Alexey N. LOTOSH Natalia Y. SELISHCHEVA Alla A. CHISTOV Alexey A. GULYAK Evgeny L. KOZHEMYAKIN Grigory L. KORSHUN Vladimir A. EFREMOV Roman G. USTINOV Alexey V. RŮŽEK Daniel EYER Luděk ALFEROVA Vera A.

  Article in Periodical

  ACS Applied Materials and Interfaces, year: 2025, volume: 17, edition: 3, DOI